Hello from GeneBe documentation | GeneBe documentation

Welcome to the documentation for GeneBe.net — a platform that allows you to easily annotate and interpret genetic variants using ACMG/AMP guidelines, with data from multiple annotation sources, including ClinVar and gnomAD.

General Help

User guide, account creation, rate limits, FAQ, and other general help topics.

GeneBe Clients: Pandas Library and Java Client

Access GeneBe using the Pandas library or the Java client.

GeneBe Hub

Variant Annotation Repository: store and share variant annotations.

ACMG Implementation

Overview of ACMG criteria and their implementation in GeneBe.

Tutorials & Quick Starts

How-to guides: annotate a VCF file or a Pandas DataFrame, parse HGVS coordinates, etc.

Bioinformatics Handbook

A quick introduction to human variant interpretation from a bioinformatics perspective.

Online Tools

HGVS converter, HG19/38 liftover tools, and more.

API Access

API endpoints and usage documentation.