TL;DR: GeneBe MCP can now work with your own data. Connect your assistant to the new signed-in URL https://mcp.genebe.net/v1/signed-in/mcp (the public one without sign-in stays), sign in to GeneBe in your browser, and ask about your samples: find them, read their phenotype, and query the variants inside, for example "rare variants in LMNA in sample X". Everything is read-only, and you decide which permissions the assistant gets.

TL;DR: GeneBe MCP is live. Add https://mcp.genebe.net/v1/mcp to Claude, ChatGPT, Cursor or VS Code, and your AI assistant can annotate and classify human genetic variants with GeneBe: an ACMG verdict with points and criteria, gnomAD frequencies, ClinVar, predictor scores and transcript consequences. It is free, read-only and needs no account.

We are happy to share that we will be attending the European Society of Human Genetics Conference 2026 (ESHG 2026).

If you are interested in constitutional CNV interpretation, ACMG/ClinGen scoring, automated variant classification, or practical integration of variant annotation tools into diagnostic and research workflows, please come by and say hello. We will be happy to meet in person, discuss examples, exchange feedback, and talk about possible use cases for GeneBe.

TL;DR: First Early Stage Release of GeneBe Desktop is out 🎉 — a local, fast, interactive browser for VCF and BED files. It supports filtering, large VCF files, Ensembl CSQ annotations, GeneBe data lookup, and runs on Windows and Linux.

TL;DR: Due to a surge in AI bot scraping (tens of millions of requests daily 🤖📈), the publications list on genebe.net 🔬 is now available only to logged-in users with confirmed emails 🔒✅. This helps protect privacy and keep the service fair for genuine researchers 🙏⚖️.